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Use of 2-pyridyl 2-acetamido-3,4,6-tri-O-acetyl-2-deoxy-1-thio-β-d-glucopyranoside as a glycosyl donor and methyl iodide as an activator for the synthesis of 1,2-trans-linked saccharides

✍ Scribed by Hari Babu Mereyala; Venugopal Reddy Gurijala


Publisher
Elsevier Science
Year
1993
Tongue
English
Weight
323 KB
Volume
242
Category
Article
ISSN
0008-6215

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Treatment of benzyl O-/?-n-galactopyranosyl-( 1+3)-2-acetamido-2-deoxy-4,6-O-isopropylidene-j3-D-glucopyranoside with tert-butylchlorodiphenylsiiane afforded the 6'-0-tert-butyldiphenylsilyl ether, which was converted into the 3',4'-0-isopropylidene derivative. Methylation and subsequent removal of