✦ LIBER ✦

ChemInform Abstract: Synthesis and Antiviral Evaluation of Enantiomeric 2′,3′-Dideoxy- and 2′,3′-Didehydro-2′,3′-dideoxy-4′-thionucleosides.

✍ Scribed by R. J. YOUNG; S. SHAW-PONTER; J. B. THOMSON; J. A. MILLER; J. G. CUMMING; A. W. PUGH; P. RIDER

Book ID: 112029401
Publisher: John Wiley and Sons
Year: 2010
Weight: 34 KB
Volume: 27
Category: Article
ISSN: 0931-7597
DOI: 10.1002/chin.199612258

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Synthesis and antiviral evaluation of en

Synthesis and antiviral evaluation of enantiomeric 2′,3′-dideoxy- and 2′,3′-didehydro-2′,3′-dideoxy-4′-thionucleosides

✍ Robert J. Young; Sue Shaw-Ponter; Jamie B. Thomson; J.Allen Miller; John G. Cumm 📂 Article 📅 1995 🏛 Elsevier Science 🌐 English ⚖ 325 KB

The synthesis and antiviral evaluation of 2',3'-dideoxy and 2',3'-didehydro-2',3'-dideoxy 4'thionucleosides in both enantiomeric series are described. Enantiomeric 4-O-silylated-4hydroxymethyl-4-thiobutyrolactones, produced in high yield from chiral glycidols, provided suitable chiral synthons: phen

Stereoselective Synthesis and Antiviral

Stereoselective Synthesis and Antiviral Activity of d -2‘,3‘-Didehydro-2‘,3‘-dideoxy-2‘-fluoro-4‘-thionucleosides

✍ Chong, Youhoon; Choo, Hyunah; Choi, Yongseok; Mathew, Judy; Schinazi, Raymond F. 📂 Article 📅 2002 🏛 American Chemical Society 🌐 English ⚖ 265 KB

ChemInform Abstract: Synthesis and Antiv

ChemInform Abstract: Synthesis and Antiviral Evaluation of α-D-2′-3′-Didehydro-2′,3′-dideoxy-3′-C-hydroxymethyl Nucleosides.

✍ Kohei Yamada; Hiroyuki Hayakawa; Shinji Sakata; Noriyuki Ashida; Yuichi Yoshimur 📂 Article 📅 2011 🏛 John Wiley and Sons ⚖ 34 KB 👁 1 views

Asymmetric Synthesis and Antiviral Activ

Asymmetric Synthesis and Antiviral Activities of l -Carbocyclic 2‘,3‘-Didehydro-2‘,3‘-dideoxy and 2‘,3‘-Dideoxy Nucleosides

✍ Wang, Peiyuan; Gullen, Beth; Newton, M. Gary; Cheng, Yung-Chi; Schinazi, Reymond 📂 Article 📅 1999 🏛 American Chemical Society 🌐 English ⚖ 142 KB

ChemInform Abstract: Stereoselective Syn

ChemInform Abstract: Stereoselective Synthesis of β-L-2′-3′-Dideoxy- and L-2′,3′-Didehydro-2′,3′-dideoxy Purine Nucleosides.

✍ Peiyuan Wang; Pascal J. Bolon; M. Gary Newton; Chung K. Chua 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 35 KB 👁 1 views

Synthesis and antiviral evaluation of α-

Synthesis and antiviral evaluation of α-d-2′,3′-didehydro-2′,3′-dideoxy-3′-C-hydroxymethyl nucleosides

✍ Kohei Yamada; Hiroyuki Hayakawa; Shinji Sakata; Noriyuki Ashida; Yuichi Yoshimur 📂 Article 📅 2010 🏛 Elsevier Science 🌐 English ⚖ 427 KB

We have identified a selective S(N)2' reaction triggered by iodide ion that leads to the ring-opening of 2,2'-anhydro-α-nucleosides. By applying the method, we have synthesized α-D-2',3'-didehydro-2',3'-dideoxy-3'-C-hydroxymethyl nucleosides, designed as potential antiviral agents.