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ChemInform Abstract: Sulfonylureido Thiazoles as Fructose-1,6-bisphosphatase Inhibitors for the Treatment of Type-2 Diabetes.

โœ Scribed by Eric Kitas; et al. et al.

Publisher
John Wiley and Sons
Year
2010
Weight
20 KB
Volume
41
Category
Article
ISSN
0931-7597

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ChemInform Abstract: The Asymmetric Synt
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## Abstract Key step in the improved synthetic pathway to sitagliptin (VII), a new DPPโ€IV inhibitor for the treatment of type 2 diabetes mellitus, is an asymmetric Michael addition to give intermediate (IV).