## a b s t r a c t We report the synthesis and in vitro activity of a series of novel substituted N-{3-[(1,1-dioxido-1,2benzothiazol-3-yl)(phenyl)amino]propyl}benzamide analogs. These analogs showed potent inhibitory activity against Kv1.3. Several demonstrated similar potency to the known Kv1.3 i
ChemInform Abstract: Substituted N-{3-[(1,1-Dioxido-1,2-benzothiazol-3-yl)(phenyl)amino]propyl}benzamide Analogues as Potent Kv1.3 Ion Channel Blockers. Part 2.
β Scribed by Curt D. Haffner; et al. et al.
- Book ID
- 102054872
- Publisher
- John Wiley and Sons
- Year
- 2011
- Weight
- 22 KB
- Volume
- 42
- Category
- Article
- ISSN
- 0931-7597
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β¦ Synopsis
Abstract
A series of substituted 3βaminoβ1,2βbenzothiazole dioxides (I) is designed and synthesized.
π SIMILAR VOLUMES
We report the synthesis and in vitro activity of a series of novel N-{3-[(1,1-dioxido-1,2-benzothiazol-3-yl)(phenyl)amino]propyl}benzamide analogs. These analogs showed potent inhibitory activity against Kv1.3. Several compounds, including compound 8b, showed similar potency to the known Kv1.3 inhib
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