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ChemInform Abstract: Synthesis and Structure—Activity Relationships of 2-(Substituted phenyl)-3-[3-(N,N-dimethylamino)propyl]-1,3-thiazolidin-4-ones Acting as H1-Histamine Antagonists.

✍ Scribed by M. Vittoria Diurno; Orazio Mazzoni; Gaetano Correale; Isabel Gomez Monterrey; Antonio Calignano; Giovanna La Rana; Adele Bolognese


Publisher
John Wiley and Sons
Year
2010
Weight
33 KB
Volume
31
Category
Article
ISSN
0931-7597

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ChemInform Abstract: Synthesis and Pharm
✍ M. V. DIURNO; O. MAZZONI; F. CAPASSO; A. A. IZZO; A. BOLOGNESE 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 29 KB

Synthesis and Pharmacological Activity of 2-(Substituted Phenyl)-3-(2 or 3-((4-Substituted Phenyl-4-hydroxy)piperidino)ethyl or propyl)-1,3-thiazolidin-4-ones. -A new series of 1,3-thiazolidinone analogues of loperamide (cf. (IV), 10 examples) are synthesized and evaluated for their antidiarrheal a