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ChemInform Abstract: Structure-Based Inhibitors of Influenza Virus Sialidase. A Benzoic Acid Lead with Novel Interaction.

โœ Scribed by S. SINGH; M. J. JEDRZEJAS; G. M. AIR; M. LUO; W. G. LAVER; W. J. BROUILLETTE


Book ID
112024084
Publisher
John Wiley and Sons
Year
2010
Weight
29 KB
Volume
26
Category
Article
ISSN
0931-7597

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ChemInform Abstract: Chemoenzymatic Synt
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Chemoenzymatic Synthesis of an N-Acetylneuraminic Acid Analogue Having a Carbamoylmethyl Group at C-4 as an Inhibitor of Sialidase from Influenza Virus. -The synthetic strategy for the preparation of the title analogue (XVI) requires the key intermediate (XII) which is synthesized by the Neu5Ac aldo