The 9-amino or 9-N-acyl-5-trifluoroacetyl methyl alpha-ketosides (1a-c) and their 2,3-didehydro analogs (2a-c) have been synthesized through Neu5Ac aldolase-catalyzed aldol reaction of 6-azido-2-benzyloxycarbonylamino-2-deoxy-D-mannose with sodium pyruvate. The six compounds were investigated as inh
โฆ LIBER โฆ
ChemInform Abstract: Chemoenzymatic Synthesis of Neuraminic Acid Analogues Structurally Varied at C-5 and C-9 as Potential Inhibitors of the Sialidase from Influenza Virus.
โ Scribed by M. MURAKAMI; K. IKEDA; K. ACHIWA
- Book ID
- 112030643
- Publisher
- John Wiley and Sons
- Year
- 2010
- Weight
- 36 KB
- Volume
- 27
- Category
- Article
- ISSN
- 0931-7597
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