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ChemInform Abstract: Structure-Based Design of Peptidomimetic Ligands of the Grb2-SH2 Domain.

โœ Scribed by J. SCHOEPFER; B. GAY; G. CARAVATTI; C. GARCIA-ECHEVERRIA; H. FRETZ; J. RAHUEL; P. FURET

Publisher
John Wiley and Sons
Year
2010
Weight
32 KB
Volume
30
Category
Article
ISSN
0931-7597

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ChemInform Abstract: Highly Potent Inhib
ChemInform Abstract: Highly Potent Inhibitors of the Grb2-SH2 Domain.
โœ Joseph Schoepfer; Heinz Fretz; Brigitte Gay; Pascal Furet; Carlos Garcia-Echever ๐Ÿ“‚ Article ๐Ÿ“… 2010 ๐Ÿ› John Wiley and Sons โš– 30 KB ๐Ÿ‘ 2 views

Highly Potent Inhibitors of the Grb2-SH2 Domain. -The preparation of peptide mimetics (IX) (11 examples) with different substituents at the 3-indolyl-propylamine C-terminal group and their inhibition of the Grb2-SH2 domain is reported.