ChemInform Abstract: Macrocyclization in the Design of a Conformationally Constrained Grb2 SH2 Domain Inhibitor.
β Scribed by Yang Gao; Johannes Voigt; Jane X. Wu; Dajun Yang; Terrence R. Burke Jr.
- Publisher
- John Wiley and Sons
- Year
- 2010
- Weight
- 27 KB
- Volume
- 32
- Category
- Article
- ISSN
- 0931-7597
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π SIMILAR VOLUMES
Highly Potent Inhibitors of the Grb2-SH2 Domain. -The preparation of peptide mimetics (IX) (11 examples) with different substituents at the 3-indolyl-propylamine C-terminal group and their inhibition of the Grb2-SH2 domain is reported.
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