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ChemInform Abstract: Convergent Synthesis of Potent Peptide Inhibitors of the Grb2-SH2 Domain by Palladium Catalyzed Coupling of a Terminal Alkyne.

✍ Scribed by Joseph Schoepfer; Brigitte Gay; Nicole End; Evelyne Muller; Gisela Scheffel; Giorgio Caravatti; Pascal Furet

Publisher
John Wiley and Sons
Year
2010
Weight
32 KB
Volume
32
Category
Article
ISSN
0931-7597

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✦ Synopsis

Abstract

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a β€œFull Text” option. The original article is trackable via the β€œReferences” option.

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ChemInform Abstract: Highly Potent Inhib
ChemInform Abstract: Highly Potent Inhibitors of the Grb2-SH2 Domain.
✍ Joseph Schoepfer; Heinz Fretz; Brigitte Gay; Pascal Furet; Carlos Garcia-Echever πŸ“‚ Article πŸ“… 2010 πŸ› John Wiley and Sons βš– 30 KB πŸ‘ 2 views

Highly Potent Inhibitors of the Grb2-SH2 Domain. -The preparation of peptide mimetics (IX) (11 examples) with different substituents at the 3-indolyl-propylamine C-terminal group and their inhibition of the Grb2-SH2 domain is reported.