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ChemInform Abstract: Structure-Based Design of Peptidomimetic Antagonists of P56lck SH2 Domain.

โœ Scribed by Christopher J. Hobbs; et al. et al.

Publisher
John Wiley and Sons
Year
2010
Weight
32 KB
Volume
33
Category
Article
ISSN
0931-7597

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Design and Synthesis of 1,4-Diazabicyclo[4.3.0]nonane Peptidomimetic Endothelin Antagonists. -Four peptidomimetics such as (XI) are synthesized in order to examine the effect of the carboxyl group stereochemistry on the biological activity. The structures of the peptidomimetics are based on the pep