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ChemInform Abstract: Stereoselective 1,4-Addition of Grignard Reagents to α,β-Enamides Using a Combined Chiral Auxiliary-Catalyst Approach.

✍ Scribed by Kallolmay Biswas; Simon Woodward


Publisher
John Wiley and Sons
Year
2008
Weight
42 KB
Volume
39
Category
Article
ISSN
0931-7597

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Abstract

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✍ Giuliana Cardillo; Luca Gentilucci; Alessandra Tolomelli; Claudia Tomasini 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 32 KB 👁 1 views

Asymmetric 1,4 Addition of Grignard Reagents to Chiral α,β-Unsaturated Esters in the Presence of Lewis Acids. -The reaction proceeds with good yields but variable diastereoselectivities, depending on the organometallic reagent and Lewis acid used. -(CARDILLO, GIULIANA;