ChemInform Abstract: Asymmetric 1,4 Addition of Grignard Reagents to Chiral α,β-Unsaturated Esters in the Presence of Lewis Acids.
✍ Scribed by Giuliana Cardillo; Luca Gentilucci; Alessandra Tolomelli; Claudia Tomasini
- Publisher
- John Wiley and Sons
- Year
- 2010
- Weight
- 32 KB
- Volume
- 30
- Category
- Article
- ISSN
- 0931-7597
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✦ Synopsis
Asymmetric 1,4 Addition of Grignard Reagents to Chiral α,β-Unsaturated Esters in the Presence of Lewis Acids.
-The reaction proceeds with good yields but variable diastereoselectivities, depending on the organometallic reagent and Lewis acid used. -(CARDILLO, GIULIANA;
📜 SIMILAR VOLUMES
Addition of Thiols to α,β-Unsaturated Esters in the Presence of Alumina. -Michael-type additions of thiols to α,β-unsaturated esters in the presence of neutral alumina proceed easily under appropriate mild conditions to give the corresponding adducts [cf. (III), (VI)/(VII)] in good to excellent yie
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