Catalytic Enantioselective Conjugate Addition of Grignard Reagents to Cyclic α,β-Unsaturated Carbonyl Compounds. -The outcome of the title reaction is influenced by many factors such as amount and structure of the chiral phosphine, copper salt, Grignard reagent, as well as the solvent used.
ChemInform Abstract: Chiral Phosphine—Phosphite Ligands in the Enantioselective 1,4-Addition of Grignard Reagents to α,β-Unsaturated Carbonyl Compounds.
✍ Scribed by Qaseem Naeemi; Tobias Robert; Darius P. Kranz; Janna Velder; Hans-Guenther Schmalz
- Publisher
- John Wiley and Sons
- Year
- 2011
- Weight
- 32 KB
- Volume
- 42
- Category
- Article
- ISSN
- 0931-7597
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
Asymmetric 1,4 Addition of Grignard Reagents to Chiral α,β-Unsaturated Esters in the Presence of Lewis Acids. -The reaction proceeds with good yields but variable diastereoselectivities, depending on the organometallic reagent and Lewis acid used. -(CARDILLO, GIULIANA;
Enantioselective Copper-Catalyzed 1,4-Addition of Organozinc Reagents to Enones Using Chiral Oxazoline-Phosphite Ligands. -The enantioselective 1,4-addition of organozinc reagents to α,β-unsaturated ketones in the presence of chiral P,N-ligands (I) with a binaphthyl phosphite group and an oxazoline