๐”– Bobbio Scriptorium
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ChemInform Abstract: Novel Aryloxyalkylthioimidazoles as Inhibitors of Acyl-CoA: Cholesterol-O-acyltransferase.

โœ Scribed by M. BANI; R. BORMETTI; W. CECCARELLI; R. FIOCCHI; M. GOBETTI; M. LOMBROSO; S. MAGNETTI; V. OLGIATI; M. PALLADINO; M. VILLA; E. VANOTTI


Book ID
112023359
Publisher
John Wiley and Sons
Year
2010
Weight
30 KB
Volume
26
Category
Article
ISSN
0931-7597

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Acyl-CoA:cholesterol acyltransferase (E.C.2.3.1.26, ACAT) is a microsomial enzyme that catalyses the formation of cholesteryl esters by acylation of cholesterol with long chain fatty acylCoA [1]. ACAT plays important roles in cellular homeostasis and in the early stages of atherosclerosis. Therefor