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ChemInform Abstract: N-Aminoindoline Derivatives as Inhibitors of 5-Lipoxygenase.

✍ Scribed by Corinne Audouin; Nathalie Mestdagh; Marie-Agnes Lassoie; Raymond Houssin; Jean-Pierre Henichart

Publisher: John Wiley and Sons
Year: 2010
Weight: 27 KB
Volume: 32
Category: Article
ISSN: 0931-7597
DOI: 10.1002/chin.200127118

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## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable v

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Synthesis of CMI-977, a Potent 5-Lipoxygenase Inhibitor. -A facile large-scale synthesis of the potent 5-lipoxygenase inhibitor CMI-977 (XI) in enantiomerically pure form starting from hydroxymethyl-γ-butyrolactone (I) derived from (S)-glutamic acid is described (yields given in g). -(CAI,