N-Hydroxyurea and Hydroxamic Acid Inhibitors of Cyclooxygenase and 5-Lipoxygenase. -Among the prepared two series of N-hydroxyurea (XII) and hydroxamic acids (XVIII) potent both COX and 5-LO inhibitors are evaluated. The desired long duration inhibition of 5-LO could not be achieved. - (CONNOLLY,
ChemInform Abstract: Structure-Activity Relationships of N-Hydroxyurea 5-Lipoxygenase Inhibitors.
โ Scribed by A. O. STEWART; P. A. BHATIA; J. G. MARTIN; J. B. SUMMERS; K. E. RODRIQUES; M. B. MARTIN; J. H. HOLMS; J. L. MOORE; R. A. CRAIG; T. KOLASA; J. D. RATAJCZYK; H. MAZDIYASNI; F. A. J. KERDESKY; S. L. DENINNO; R. G. MAKI; J. B. BOUSKA; P. R. YOUNG; C. LANNI; R. L. BELL; G. W. CARTER; C. D. W. BROOKS
- Publisher
- John Wiley and Sons
- Year
- 2010
- Weight
- 33 KB
- Volume
- 28
- Category
- Article
- ISSN
- 0931-7597
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