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ChemInform Abstract: Inhibitors of the Interactions Between HIV-1 IN and the Cofactor LEDGF/p75

✍ Scribed by Laura De Luca; Stefania Ferro; Francesca Morreale; Sara De Grazia; Alba Chimirri

Publisher
John Wiley and Sons
Year
2011
Weight
18 KB
Volume
42
Category
Article
ISSN
0931-7597

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The Synthesis and Evaluation of Cyclic Ureas as HIV Protease Inhibitors: Modifications of the P1/P1' Residues. -Among various novel cyclic ureas compounds (VIII) show improved antiviral activity against HIV compared with the lead compounds DMP 323 and DMP 450. -(PATEL,