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ChemInform Abstract: Derivatization of the C-12—C-13 Functional Groups of Epothilones A, B and C.

✍ Scribed by Michael Sefkow; Michael Kiffe; Gerhard Hoefle

Publisher
John Wiley and Sons
Year
2010
Weight
32 KB
Volume
30
Category
Article
ISSN
0931-7597

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ChemInform Abstract: Chiral Synthesis of
ChemInform Abstract: Chiral Synthesis of the C3-13 Segment of Epothilone A.
✍ Z.-Y. LIU; C.-Z. YU; J.-D. YANG 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 32 KB 👁 1 views

Chiral Synthesis of the C 3-13 Segment of Epothilone A. -Epothilones represent a new class of macrolides showing all the biological effects of taxol, but their structure is totally different. On route to an epothilone A synthesis, the preparation of the C 3 -C 13 segment (V) from inexpensive gerani