ChemInform Abstract: Synthesis of the C(
ChemInform Abstract: Synthesis of the C(11)โC(20) Segment of the Cytotoxic Macrolide Epothilone B.
โ
J. MULZER; A. MANTOULIDIS; E. OEHLER
๐
Article
๐
2010
๐
John Wiley and Sons
โ 32 KB
Synthesis of the C(11)-C(20) Segment of the Cytotoxic Macrolide Epothilone B. -The fragment (VIII) is synthesized from (S)-malic acid (I) via 2 Wittig reactions and a Sharpless asymmetric epoxidation. -