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ChemInform Abstract: Synthesis of the C(1)-C(9) Segment of the Cytotoxic Macrolides Epothilon A and B.

โœ Scribed by J. MULZER; A. MANTOULIDIS


Publisher
John Wiley and Sons
Year
2010
Weight
32 KB
Volume
28
Category
Article
ISSN
0931-7597

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ChemInform Abstract: Chiral Synthesis of
โœ Z.-Y. LIU; C.-Z. YU; J.-D. YANG ๐Ÿ“‚ Article ๐Ÿ“… 2010 ๐Ÿ› John Wiley and Sons โš– 32 KB

Chiral Synthesis of the C 3-13 Segment of Epothilone A. -Epothilones represent a new class of macrolides showing all the biological effects of taxol, but their structure is totally different. On route to an epothilone A synthesis, the preparation of the C 3 -C 13 segment (V) from inexpensive gerani