𝔖 Bobbio Scriptorium
✦   LIBER   ✦

ChemInform Abstract: Antiproliferative Hybrid Analogues of the Hormone 1α,25- Dihydroxyvitamin D3: Design, Synthesis, and Preliminary Biological Evaluation.

✍ Scribed by G. H. POSNER; J. K. LEE; M. C. WHITE; R. H. HUTCHINGS; H. DAI; J. L. KACHINSKI; P. DOLAN; T. W. KENSLER


Publisher
John Wiley and Sons
Year
2010
Weight
37 KB
Volume
28
Category
Article
ISSN
0931-7597

No coin nor oath required. For personal study only.


📜 SIMILAR VOLUMES


ChemInform Abstract: Noncalcemic, Antipr
✍ G. H. POSNER; J. K. LEE; Q. WANG; S. PELEG; M. BURKE; H. BREM; P. DOLAN; T. W. K 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 45 KB 👁 1 views

## Noncalcemic, Antiproliferative, Transcriptionally Active, 24-Fluorinated Hybrid Analogues of the Hormone 1α,25-Dihydroxyvitamin D 3 . Synthesis and Preliminary Biological Evaluation. -New analogues (XII) of the title hormone are synthesized as mixtures of two diastereomers, which are subseque

ChemInform Abstract: Synthesis and Biolo
✍ Jun-ichi Oshida; Makoto Okamoto; Seiichi Ishizuka; Shizuo Azuma 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 35 KB 👁 1 views

Synthesis and Biological Evaluation of 1α,24-Dihydroxy-25nitrovitamin D 3 . -The synthesis of an active vitamin D 3 analogue (X), proceeding via palladium-catalyzed alkylative enyne reaction, is described. The corresponding 24(S)-isomer is found to be tenfold less potent than (X).