An Efficient Synthesis of (-)-Pestalotin and Its Enantiomer Using Sharpless Asymmetric Dihydroxylation. -The title compound (IV), a gibberellin synergist isolated from a phytopathogenic fungus Pestaltia cryptomeriaecola, is prepared using Sharpless asymmetric dihydroxylation as the key step. A simi
ChemInform Abstract: A Short and Efficient Synthesis of Phytosphingosines Using Asymmetric Dihydroxylation.
β Scribed by R. IMASHIRO; O. SAKURAI; T. YAMASHITA; H. HORIKAWA
- Publisher
- John Wiley and Sons
- Year
- 2010
- Weight
- 42 KB
- Volume
- 29
- Category
- Article
- ISSN
- 0931-7597
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## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a βFull Textβ option. The original article is trackable v
The synthesis of the title compound (VI), a brasilane sesquiterpenoid alcohol, is achieved from the (R)-pulegone derivative (I) in only three steps. The key to success is the diastereoselective radical addition of the tertiary radical derived from (II) to the electrophilic radicophile (I). -(COSSY,