ChemInform Abstract: A Very Short and Efficient Synthesis of (+)-Conocephalenol.

✍ Scribed by J. COSSY; S. BOUZBOUZ; A. HAKIKI

• Publisher: John Wiley and Sons
• Year: 2010
• Weight: 29 KB
• Volume: 29
• Category: Article
• ISSN: 0931-7597
• DOI: 10.1002/chin.199812161

✦ Synopsis

The synthesis of the title compound (VI), a brasilane sesquiterpenoid alcohol, is achieved from the (R)-pulegone derivative (I) in only three steps. The key to success is the diastereoselective radical addition of the tertiary radical derived from (II) to the electrophilic radicophile (I). -(COSSY,