ChemInform Abstract: A New Route to 1,1-Difluoroolefins from Carboxylic Acids.
β Scribed by K.-I. KIM; J. R. MCCARTHY
- Book ID
- 112035895
- Publisher
- John Wiley and Sons
- Year
- 2010
- Weight
- 31 KB
- Volume
- 27
- Category
- Article
- ISSN
- 0931-7597
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π SIMILAR VOLUMES
The transformation of bromides (I) (prepared via a previously reported reaction of aldehydes/ketones with difluorovinyllithium) to (III) and ( VI) represents a general and highly regioselective methodology for the introduction of a difluorovinylic group. The silylated products (VI) are useful precur
A new method for the synthesis of various l,l-difluoroolefins is described. The key step is the treaUnent of l-bromo-l,l-difluoro-2-alkenes with organo-raetallic reagents in the presence of copper and lithium salts.
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