Disubstituted homopropargylic alcohols can be prepared inversion through the intermediate formation of a bromoallenol moiety. in a diastereodivergent fashion starting from propargylic epoxides by BF 3 -catalysed direct ring-opening or by double served. Thus disubstituted anti homopropargylic alcohol
ChemInform Abstract: A New Diastereodivergent Synthesis of 1,2-Disubstituted Homopropargylic Alcohols.
β Scribed by Fabrice Chemla; Nicolas Bernard; Jean Normant
- Publisher
- John Wiley and Sons
- Year
- 2010
- Weight
- 38 KB
- Volume
- 30
- Category
- Article
- ISSN
- 0931-7597
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
A Stereospecific Synthesis of 1,2-Disubstituted Homopropargylic Protected Alcohols from Bromoallenols. -Bromoallenols [cf. (I)] or the related ethers [cf. (V)] undergo a stereospecific reaction with organocopper or Grignard reagents providing 1,2-disubstituted derivatives (III) and (VII).
## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a βFull Textβ option. The original article is trackable v