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ChemInform Abstract: Lewis Acid Mediated Ring Opening of Propargylic Epoxides: A Stereospecific Synthesis of 1,2-Disubstituted Homopropargylic Alcohols.

โœ Scribed by N. BERNARD; F. CHEMLA; J. F. NORMANT


Publisher
John Wiley and Sons
Year
2010
Weight
30 KB
Volume
29
Category
Article
ISSN
0931-7597

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ChemInform Abstract: A Stereospecific Sy
โœ Nicolas Bernard; Fabrice Chemla; Jean F. Normant ๐Ÿ“‚ Article ๐Ÿ“… 2010 ๐Ÿ› John Wiley and Sons โš– 28 KB ๐Ÿ‘ 1 views

A Stereospecific Synthesis of 1,2-Disubstituted Homopropargylic Protected Alcohols from Bromoallenols. -Bromoallenols [cf. (I)] or the related ethers [cf. (V)] undergo a stereospecific reaction with organocopper or Grignard reagents providing 1,2-disubstituted derivatives (III) and (VII).