๐”– Bobbio Scriptorium
โœฆ   LIBER   โœฆ

ChemInform Abstract: A Convergent Approach to Functionalized Alkynes.

โœ Scribed by J. BOIVIN; S. HUPPE; S. Z. ZARD

Publisher
John Wiley and Sons
Year
2010
Weight
34 KB
Volume
28
Category
Article
ISSN
0931-7597

No coin nor oath required. For personal study only.

โœฆ Synopsis

The convergent approach to a broad variety of functionalized alkynes starts with a Knoevenagel-type condensation of 4-unsubstituted isoxazolines with ketones or aldehydes. The resulting adducts are subjected to Michael addition with various nucleophiles such as hydride, cyanide or phosphite. Exposure of these products to sodium nitrite/ferrous sulfate in aqueous acetic acid finally provides the alkynes. -(BOIVIN,

๐Ÿ“œ SIMILAR VOLUMES

A New Convergent Approach to ฮฑ-Branched
A New Convergent Approach to ฮฑ-Branched Alkynes.
โœ Delphine Renard; Hadi Rezaei; Samir Z. Zard ๐Ÿ“‚ Article ๐Ÿ“… 2010 ๐Ÿ› John Wiley and Sons โš– 31 KB

## Abstract For Abstract see ChemInform Abstract in Full Text.

ChemInform Abstract: A Convergent Approa
ChemInform Abstract: A Convergent Approach to Indolines and Indans.
โœ Thi-My Ly; Beatrice Quiclet-Sire; Benoit Sortais; Samir Z. Zard ๐Ÿ“‚ Article ๐Ÿ“… 2010 ๐Ÿ› John Wiley and Sons โš– 29 KB ๐Ÿ‘ 2 views

A Convergent Approach to Indolines and Indans. -Indolines and indans are available by radical addition of xanthates (II) to N-allylanilides (I) or a substituted 4-aryl-1-butene (V) followed by cyclization onto the aromatic ring.