ChemInform Abstract: A Convergent Approa
✍
J. BOIVIN; S. HUPPE; S. Z. ZARD
📂
Article
📅
2010
🏛
John Wiley and Sons
⚖ 34 KB
👁 1 views
The convergent approach to a broad variety of functionalized alkynes starts with a Knoevenagel-type condensation of 4-unsubstituted isoxazolines with ketones or aldehydes. The resulting adducts are subjected to Michael addition with various nucleophiles such as hydride, cyanide or phosphite. Exposur