ChemInform Abstract: A Convergent Approa
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J. BOIVIN; S. HUPPE; S. Z. ZARD
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Article
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2010
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John Wiley and Sons
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The convergent approach to a broad variety of functionalized alkynes starts with a Knoevenagel-type condensation of 4-unsubstituted isoxazolines with ketones or aldehydes. The resulting adducts are subjected to Michael addition with various nucleophiles such as hydride, cyanide or phosphite. Exposur