The base-pairing properties of oligonucleotides containing the unusual N 8 -linked 8-aza-7-deazaadenine 2'deoxyribonucleoside (2a) as well as its 7-bromo derivative 2b are described. The oligonucleotides were prepared by solid-phase synthesis employing phosphoramidite chemistry. Compound 2a forms a
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ChemInform Abstract: 8-Aza-7-deazaadenine and 7-Deazaguanine: Synthesis and Properties of Nucleosides and Oligonucleotides with Nucleobases Linked at Position-8
β Scribed by F. Seela; H. Debelak
- Publisher
- John Wiley and Sons
- Year
- 2010
- Weight
- 26 KB
- Volume
- 32
- Category
- Article
- ISSN
- 0931-7597
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