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ChemInform Abstract: Duplex Stability of Oligonucleotides Containing 7-Substituted 7-Deaza- and 8-Aza-7-deazapurine Nucleosides.

✍ Scribed by F. SEELA; N. RAMZAEVA; M. ZULAUF

Publisher
John Wiley and Sons
Year
2010
Weight
29 KB
Volume
29
Category
Article
ISSN
0931-7597

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ChemInform Abstract: 8-Aza-7-deazapurine
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## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a β€œFull Text” option. The original article is trackable v

Oligonucleotides Containing Pyrazolo[3,4
Oligonucleotides Containing Pyrazolo[3,4-d]pyrimidines: The Influence of 7-Substituted 8-Aza-7-deaza-2β€²-deoxyguanosines on the Duplex Structure and Stability
✍ Frank Seela; Georg Becher πŸ“‚ Article πŸ“… 1999 πŸ› John Wiley and Sons 🌐 German βš– 186 KB

Oligonucleotides containing 7-substituted 8-aza-7-deazaguanines ( 6-amino-1,5-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-ones) were prepared by automated solid-phase synthesis. A series of 7-alkynylated 8aza-7-deaza-2'-deoxyguanosines (see 4a Β± d) were synthesized with the 7-iodonucleoside 3c as starting