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ChemInform Abstract: 5,6-Dihydropyran-2-ones Possessing Various Sulfonyl Functionalities: Potent Nonpeptidic Inhibitors of HIV Protease.

✍ Scribed by Frederick E. Boyer; et al. et al.

Publisher
John Wiley and Sons
Year
2010
Weight
36 KB
Volume
31
Category
Article
ISSN
0931-7597

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✦ Synopsis

Abstract

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a β€œFull Text” option. The original article is trackable via the β€œReferences” option.

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Nonpeptidic HIV Protease Inhibitors: 6-Alkyl-5,6-dihydropyran-2-ones Possessing a Novel and Achiral 3-(2-t-Butyl-5-methyl-4sulfamate)phenylthio Moiety. -With the introduction of a sulfamate moiety, a new template is created which shows HIV protease binding affinity. An alkyl group at the 6-position