ChemInform Abstract: Nonpeptidic HIV Protease Inhibitors: 6-Alkyl-5,6-dihydropyran-2-ones Possessing Achiral 3-(4-Amino/carboxamide-2-t-butyl, 5-Methylphenyl thio) Moiety: Antiviral Activities and Pharmacokinetic Properties.

ChemInform Abstract: Nonpeptidic HIV Pro

ChemInform Abstract: Nonpeptidic HIV Protease Inhibitors: 6-Alkyl-5,6-dihydropyran-2-ones Possessing a Novel and Achiral 3-(2-t-Butyl-5-methyl-4-sulfamate)phenylthio Moiety.

✍ J. V. N. Vara Prasad; et al. et al. 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 33 KB 👁 1 views

Nonpeptidic HIV Protease Inhibitors: 6-Alkyl-5,6-dihydropyran-2-ones Possessing a Novel and Achiral 3-(2-t-Butyl-5-methyl-4sulfamate)phenylthio Moiety. -With the introduction of a sulfamate moiety, a new template is created which shows HIV protease binding affinity. An alkyl group at the 6-position