ChemInform Abstract: 4-Cyano-2-butenyl Group: A New Type of Protecting Group in Oligonucleotide Synthesis via Phosphoramidite Approach.
โ Scribed by V. T. RAVIKUMAR; Z. S. CHERUVALLATH; D. L. COLE
- Book ID
- 112041732
- Publisher
- John Wiley and Sons
- Year
- 2010
- Weight
- 25 KB
- Volume
- 27
- Category
- Article
- ISSN
- 0931-7597
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๐ SIMILAR VOLUMES
4-Cyano-2-butenyl (CB) is a new type of protecting group for the intemucleotidic bonds in the synthesis of oligodeoxyribonucleotides by the phosphoramidite approach. This group is stable to acidic conditions and can be removed under mild conditions by a 8-elimination pathway using aqueous ammonium h
Absbwct: 2-Diphenylmethylsilylethyl (DPSE) is a new protecting group for internucleotidic bonds in the synthesis of oligodeoqribo nucleotides by the phosphoramidite approach. This group is stable to acidic conditions and can be removed under mild /3$ragmentation conditions using aqueous ammonium hyd