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ChemInform Abstract: 4-Cyano-2-butenyl Group: A New Type of Protecting Group in Oligonucleotide Synthesis via Phosphoramidite Approach.

โœ Scribed by V. T. RAVIKUMAR; Z. S. CHERUVALLATH; D. L. COLE


Book ID
112041732
Publisher
John Wiley and Sons
Year
2010
Weight
25 KB
Volume
27
Category
Article
ISSN
0931-7597

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4-Cyano-2-butenyl (CB) is a new type of protecting group for the intemucleotidic bonds in the synthesis of oligodeoxyribonucleotides by the phosphoramidite approach. This group is stable to acidic conditions and can be removed under mild conditions by a 8-elimination pathway using aqueous ammonium h

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