Chemical synthesis of β-L-fucopyranosyl phosphate and β-L-rhamnopyranosyl phosphate
✍ Scribed by Prihar, H. S.; Behrman, E. J.
- Book ID
- 126235084
- Publisher
- American Chemical Society
- Year
- 1973
- Tongue
- English
- Weight
- 774 KB
- Volume
- 12
- Category
- Article
- ISSN
- 0006-2960
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📜 SIMILAR VOLUMES
A practical 15-mmol large-scale synthesis of beta-L-fucopyranosyl dicyclohexylammonium phosphate from L-fucose in 63% overall yield was developed. The synthesis took advantage of a neighboring Bz-2 group participating in a Koenigs-Knorr-like glycosylation. The sugar phosphate was transformed into th
## Abstract Reaction of the benzyl‐ and acetyl‐protected α‐trichloroacetimidates 1 and 6α with dialkyl and diaryl phosphates in the presence of traces of acid affords stereoelectively the thermodynamically more stable α‐L‐fucopyranosyl phosphates 2, 7 and 8, respectively, in high yields. The use of