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Characterization of three t(3;8)(q27;q24) translocations from diffuse large B-cell lymphomas

โœ Scribed by Bertrand, P; Maingonnat, C; Picquenot, J M; Dastugue, N; Penther, D; Ysebaert, L; Maisonneuve, C; Tilly, H; Bastard, C


Book ID
110058509
Publisher
Nature Publishing Group
Year
2007
Tongue
English
Weight
176 KB
Volume
22
Category
Article
ISSN
0887-6924

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Hypermutation of the MYC gene in diffuse
โœ John F. Bradley; Paul G. Rothberg; Marc Ladanyl; R. S. K. Chaganti ๐Ÿ“‚ Article ๐Ÿ“… 1993 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 303 KB ๐Ÿ‘ 1 views

The sequence of the exon I lintron I boundary region of the MYC gene was determined in two diffuse large cell lymphomas (DLCL), one with t(8; 14) (q24q32) and the other with t(8;22) (q24;q I I). Both tumors had multiple mutations in this region. Also, both tumors had mutations in the protein binding