✦ LIBER ✦

The t(1;3)(p34;q27)translocation: a nonrandom BCL6 rearrangement in diffuse large B cell lymphoma

✍ Scribed by Nozomi Niitsu; Hirokazu Nakamine; Yuki Hagiwara; Ken Tanae; Ikuo Miura

Publisher: Springer
Year: 2007
Tongue: English
Weight: 160 KB
Volume: 87
Category: Article
ISSN: 0939-5555
DOI: 10.1007/s00277-007-0345-z

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Nonrandom fusion of L-Plastin(LCP1) and

Nonrandom fusion of L-Plastin(LCP1) and LAZ3(BCL6) genes by t(3;13)(q27;q14) chromosome translocation in two cases of B-cell non-Hodgkin lymphoma

✍ Sylvie Galiègue-Zouitina; Sabine Quief; Marie-Paule Hildebrand; Claude Denis; La 📂 Article 📅 1999 🏛 John Wiley and Sons 🌐 English ⚖ 194 KB 👁 1 views

The LAZ3(BCL6) gene on chromosome band 3q27 is nonrandomly disrupted in B-cell non-Hodgkin lymphoma (B-NHL) by chromosomal translocations clustered within a 3.3-kb MTC (major translocation cluster) located between the two first noncoding exons. These translocations generally result in the expression

t(3;14)(p14;q32) Results in aberrant exp

t(3;14)(p14;q32) Results in aberrant expression of FOXP1 in a case of diffuse large B-cell lymphoma

✍ James A. L. Fenton; Ed Schuuring; Sharon L. Barrans; Alison H. Banham; Sara J. R 📂 Article 📅 2005 🏛 John Wiley and Sons 🌐 English ⚖ 253 KB

## Abstract Strong expression of Forkhead box‐P1 (FOXP1), a winged‐helix transcription factor, has been identified as an independent prognostic factor in diffuse large B‐cell lymphoma (DLBCL). However, possible mechanisms of deregulation of this gene, on 3p14.1, have yet to be elucidated. We have i