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Characterization of the Chemoenzymatic Synthesis of N-Acetyl-d-neuraminic Acid (Neu5Ac)

✍ Scribed by Simone Blayer; John M. Woodley; Malcolm D. Lilly; Michael J. Dawson


Book ID
109387899
Publisher
American Institute of Chemical Engineers
Year
1996
Tongue
English
Weight
211 KB
Volume
12
Category
Article
ISSN
8756-7938

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Alkaline biocatalysis for the direct syn
✍ Simone Blayer; John M. Woodley; Michael J. Dawson; Malcolm D. Lilly πŸ“‚ Article πŸ“… 1999 πŸ› John Wiley and Sons 🌐 English βš– 108 KB πŸ‘ 2 views

Integration between the alkaline epimerization of N-acetyl-D-glucosamine (GlcNAc) to N-Acetyl-Dmannosamine (ManNAc) and the N-acetyl-D-neuraminic acid (Neu5Ac) aldolase-catalyzed biotransformation has been assessed experimentally. GlcNAc epimerization took place above pH 9.0, and the initial rate of