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Characterization of the Antibiotic GE2270 Complex by Combined Liquid Chromatography and Mass Spectrometry

✍ Scribed by L. Colombo; D. Guglielmi; E. Selva; S. Stella; R. Stradi; C. Sottani; L. F. Zerilli

Publisher
John Wiley and Sons
Year
1996
Tongue
English
Weight
337 KB
Volume
10
Category
Article
ISSN
0951-4198

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✦ Synopsis

Components of GE2270 Complex, an antibiotic active against Gram-positive bacteria and anaerobes, were identified by continuous-flow fast-atom bombardment mass spectrometry and by combined liquid chromatography and mass spectrometry under electrospray and thermospray ionization conditions. Electrospray ionization seems to be the most suitable technique for the routine analysis of crude extracts of antibiotics from fermentation broths.

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