Characterization of interactions between polyphenolic compounds and human serum proteins by capillary electrophoresis
✍ Scribed by Andréa Diniz; Laura Escuder-Gilabert; Norberto P. Lopes; Rosa María Villanueva-Camañas; Salvador Sagrado; María José Medina-Hernández
- Publisher
- Springer
- Year
- 2008
- Tongue
- English
- Weight
- 444 KB
- Volume
- 391
- Category
- Article
- ISSN
- 1618-2650
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## Abstract Capillary electrophoresis (CE) analysis of human serum proteins and apolipoproteins is described and compared with sodium dodecyl sulfate‐polyacryl‐amide gel electrophoresis and cellulose acetate membrane electrophoresis. Under optimized CE conditions apolipoproteins I could be determin
The interaction between drugs and human serum albumin (HSA) was investigated by capillary electrophoresis (CE). It involves stereoselectivity, drug displacement and synergism effects. Under protein-drug binding equilibrium, the unbound concentrations of drug enantiomers were measured by frontal anal