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Characterization of human sporadic ALS biomarkers in the familial ALS transgenic mSOD1G93A mouse model

✍ Scribed by Lilo, E.; Wald-Altman, S.; Solmesky, L. J.; Ben Yaakov, K.; Gershoni-Emek, N.; Bulvik, S.; Kassis, I.; Karussis, D.; Perlson, E.; Weil, M.

Book ID
121367402
Publisher
Oxford University Press
Year
2013
Tongue
English
Weight
343 KB
Volume
22
Category
Article
ISSN
0964-6906

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The recent development of a rat model of amyotrophic lateral sclerosis (ALS) in which the rats harbor a mutated human SOD1 (G93A) gene has greatly expanded the range of potential experiments, because the rats' large size permits biochemical analyses and therapeutic trials, such as the intrathecal in