Changes in intracellular calcium concentration in response to hypertonicity in bovine articular chondrocytes
✍ Scribed by Julio C Sánchez; Robert J Wilkins
- Book ID
- 113522396
- Publisher
- Elsevier Science
- Year
- 2004
- Tongue
- English
- Weight
- 706 KB
- Volume
- 137
- Category
- Article
- ISSN
- 1095-6433
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
Chondrocytes experience a dynamic extracellular osmotic environment during normal joint loading when fluid is forced from the matrix, increasing the local proteoglycan concentration and therefore the ionic strength and osmolarity. To exist in such a challenging environment, chondrocytes must possess
The cytosolic free calcium ion concentration for mammalian cell systems is believed to be maintained within a narrow range compatible with cellular homeostasis. Growth plate chondrocytes have been shown to accumulate large quantities of calcium within their mitochondria, but the cytosolic free calci
## Abstract There are some reports that clinical application of propylene glycol (PG) induces hypertonicity and results in various toxicities. In our experiments, a hypertonic solution made by adding PG to a normal saline raised the intracellular calcium concentration ([Ca^2+^]i). The present study