Chondrocytes experience a dynamic extracellular osmotic environment during normal joint loading when fluid is forced from the matrix, increasing the local proteoglycan concentration and therefore the ionic strength and osmolarity. To exist in such a challenging environment, chondrocytes must possess
✦ LIBER ✦
Effects of hypotonic shock on intracellular pH in bovine articular chondrocytes
✍ Scribed by J.C Sánchez; R.J Wilkins
- Book ID
- 114363213
- Publisher
- Elsevier Science
- Year
- 2003
- Tongue
- English
- Weight
- 264 KB
- Volume
- 135
- Category
- Article
- ISSN
- 1095-6433
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The purpose of this study was to examine the effects of particles, derived from metals commonly used in joint prostheses, on chondrocyte proliferation, metabolism, and morphology in vitro. Chondrocyte viability was influenced by the type and concentration of metal particle added. Cobalt was toxic to