✦ LIBER ✦

Cytosolic calcium concentration in bovine growth plate chondrocytes

✍ Scribed by Andrew M. Star; Dr. Joseph P. Iannotti; Carl T. Brighton; Dr. Peter F. Armstrong

Publisher: Elsevier Science
Year: 1987
Tongue: English
Weight: 591 KB
Volume: 5
Category: Article
ISSN: 0736-0266
DOI: 10.1002/jor.1100050115

No coin nor oath required. For personal study only.

✦ Synopsis

The cytosolic free calcium ion concentration for mammalian cell systems is believed to be maintained within a narrow range compatible with cellular homeostasis. Growth plate chondrocytes have been shown to accumulate large quantities of calcium within their mitochondria, but the cytosolic free calcium concentration has not been determined. This study measures the cytosolic free ionic calcium concentration in growth plate chondrocytes using two variations of the Quin I1 fluorescence technique. The results indicate that in isolated growth plate chondrocytes, the cytosolic free ionic calcium concentration is similar to other nonmineralizing mammalian cell types (106-137 nM).

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