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Challenges in drug delivery to the brain: Nature is against us

✍ Scribed by Krol, Silke


Book ID
119291764
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
848 KB
Volume
164
Category
Article
ISSN
0168-3659

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[AAPS Advances in the Pharmaceutical Sci
✍ Hammarlund-Udenaes, Margareta; de Lange, Elizabeth C.M.; Thorne, Robert G. πŸ“‚ Article πŸ“… 2013 πŸ› Springer New York 🌐 English βš– 984 KB

The development of new CNS drugs is notoriously difficult. Drugs must reach CNS target sites for action and these sites are protected by a number of barriers, the most important being the blood –brain barrier (BBB). Many factors are therefore critical to consider for CNS drug delivery, e.g. active/p