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Controlled Release in Oral Drug Delivery || Drug Delivery to the Colon

✍ Scribed by Wilson, Clive G.; Crowley, Patrick J.

Book ID: 118043599
Publisher: Springer US
Year: 2011
Weight: 362 KB
Category: Article
ISBN: 1461410045
DOI: 10.1007/978-1-4614-1004-1_18

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The human gastrointestinal tract consists of a highly complex ecosystem of aerobic and anaerobic microorganisms that plays a significant role in the metabolism of nutrients as well as drugs. In the colon, bacteria ferment various types of substrates that are not susceptible to digestion in the small