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Cellular binding of benzo(a)pyrene to DNA characterized by low temperature fluorescence

✍ Scribed by Vesna Ivanovic; Nicholas E. Geacintov; I.Bernard Weinstein

Book ID: 118311093
Publisher: Elsevier Science
Year: 1976
Tongue: English
Weight: 468 KB
Volume: 70
Category: Article
ISSN: 0006-291X
DOI: 10.1016/0006-291x(76)91026-3

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## Abstract Individual metabolites of benzo (a)pyrene were isolated from rat liver microsomal incubation of the parent hydrocarbon, and subsequently bound to DNA in separate incubations with microsomes. Of the metabolites examined, by far the greatest binding resulted with 7,8‐dihydro‐7,8‐dihydroxy