✦ LIBER ✦

Cell-mediated cytotoxicity

✍ Scribed by Margaret K. Taylor; J.John Cohen

Publisher: Elsevier Science
Year: 1992
Tongue: English
Weight: 786 KB
Volume: 4
Category: Article
ISSN: 0952-7915
DOI: 10.1016/0952-7915(92)90086-t

No coin nor oath required. For personal study only.

✦ Synopsis

Progress is being made in determining how cytotoxic cells are activated, the way the lethal hit is delivered and the subsequent events in the target cell. Several factors cloud the issue, including the heterogeneity of cytotoxic cells, differences between fresh cells and cell lines, and the possibility of single cells using multiple cytotoxic mechanisms. The most difficult task will be to define which cytotoxic mechanisms are significant in vivo.

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