## Abstract Two syntheses of radiocarbon labelled FCE 24578, namely 2‐cyano‐3‐(1,4‐dihydro‐1‐phenyl‐[1]‐benzothiopyrano[4,3‐c]pyrazol‐3‐yl)‐3‐oxo‐N‐phenylpropanamide, are reported. The former gave, employing [1‐^14^C]acetonitrile as labelled starting material and with an overall radiochemical yield
Carbon-14 labelling of terbinafine, an antimycotic agent
✍ Scribed by Hendrik Andres
- Publisher
- John Wiley and Sons
- Year
- 1989
- Tongue
- French
- Weight
- 347 KB
- Volume
- 27
- Category
- Article
- ISSN
- 0022-2135
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
Various Carbon-I4 l a b e l l e d amino acids i n c l u d i n g t h e a r o m a t i c ones viz., t y r o s i n e , phenylalanine and t r y p t o p h a n are converted t o t h e corresponding c a r b o x y l i c acids i n high y i e l d (70 -9M) on a micromolar scale s y n t h e s i s l y r e a c t i
## Abstract Xenalipin 1 (4′‐trifluoromethyl‐2‐biphenylcarboxylic acid) was synthesized in the [^14^C]‐labelled form with specific activity 21.0 mCi/mmol suitable for metabolism and distribution studies in animals. The synthetic sequence involved conversion of [^14^C]‐ benzoic acid to the 4,4‐dimeth
## Abstract Piritrexim 1(2,4‐diamino‐6‐(2,5‐dimethoxybenzyl)‐5‐methylpyrido[2,3‐__d__]‐pyrimidine) was synthesized in the [^14^C]‐labelled form with specific activity 50.8 mCi/mmol suitable for drug metabolism, transport, dispostion and mechanism of action studies. The synthetic sequence involved s
Ropivacaine hydrochloride mnohydrab (LEA 103) is a new local anaesthetic agent which currently is u n k r preclhical and clinical investigation. The preparation of (S) -N-(2 , 6-[2-methyl-l 4C] dimthylphenyl) -1propylpipridine-2carhoxarmde ' hyamcklaride mmhydxab (6, [14C]-LeA 103) with a specific a