## Abstract The ^13^C NMR spectra were determined and signals assigned to the various carbons of veratridine and cevadine.
Carbon-13 nuclear magnetic resonance spectra of nicotine metabolites and related compounds
✍ Scribed by Toshiaki Nishida; ÅKe Pilotti; Curt R. Enzell
- Publisher
- John Wiley and Sons
- Year
- 1980
- Tongue
- English
- Weight
- 306 KB
- Volume
- 13
- Category
- Article
- ISSN
- 0749-1581
No coin nor oath required. For personal study only.
✦ Synopsis
Abstract
The potential of ^13^C NMR techniques for studies of nicotine metabolism has been investigated by acquisition and assignment of ^13^C NMR spectra of nicotine, its metabolites and some related compounds. It is shown that C‐2′ of nicotine would be the best site for ^13^C labelling when using the method to gain further insight into the metabolic pathways of nicotine.
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REFERENCE DATA causes the electron density to be comparatively lower at C-3 and C-5 than at C-2 and C-4, so that the former signals resonate at lower fields. Distinction between the signals of the C-2/C-4 and C-3/C-5 pairs was achieved by comparing the C-H coupling patterns of 5 and 1. Compounds 1,